New “Trojan horse” obesity drug supercharges weight loss in early tests
Researchers have created a next-generation obesity drug that works like a “Trojan horse,” using GLP-1/GIP signals to slip a powerful metabolic enhancer directly into target cells. In mice, it outperformed existing treatments—curbing appetite, increasing weight loss, and improving blood sugar levels. Because the extra drug acts only where it’s needed, it can be used at much lower doses, potentially
Scientists discover why Ozempic works better for some people
Some people taking Ozempic-like diabetes drugs may be getting dramatically better results for a surprising reason: why they overeat in the first place. A year-long study in Japan found that people who tend to eat because tempting food looks or smells irresistible were much more likely to lose weight and improve blood sugar levels on GLP-1 medications. But people who eat mainly in response to stres
Scientists find a way to stop dangerous belly fat as we age
Aging doesn’t just add fat—it redistributes it in risky ways, pushing more into the abdomen where it can harm health. Scientists found that testosterone plays a key role in this shift. In older women recovering from hip fractures, a testosterone gel combined with exercise helped prevent the usual rise in dangerous visceral fat. The result could point to a powerful new strategy for improving recove
Alnylam rebuked by FDA over efficacy claims on Amvuttra website
The FDA has hit Alnylam with an untitled letter over the consumer website for Amvuttra, accusing the biotech of presenting open-label data that create a misleading impression of the drug’s effects.
Insulet CEO details ‘Scrubs’ device promotion win as it boosts awareness, education drive
Insulet has always been a strong leader in the medtech industry when it comes to its marketing game—and the diabetes device maker isn’t looking to rest on its laurels.
Scientists reverse diabetes in mice with lab-grown insulin cells
Scientists in Sweden have taken a major step toward a potential cure for type 1 diabetes by developing a more reliable way to create insulin-producing cells from human stem cells. These lab-grown cells not only respond strongly to glucose but were also able to restore blood sugar control when transplanted into diabetic mice.
STAT+: Oregon hospitals won’t outsource to national physician chain after all
Faced with stiff local opposition and a possible loss in court, PeaceHealth drops plan to replace Eugene Emergency Physicians with staffing chain ApolloMD.
Trump administration’s drug strategy is at odds with recent actions on funding, policy
The White House nods to medication-assisted treatment and fentanyl test strips, despite recently placing new limits.
STAT+: Administration report on most favored nation drug pricing raises new details — and questions
Administration report on most-favored nation drug pricing raises new details — and questions.
STAT+: Sanofi asks to pull diabetes drug out of FDA voucher program after political appointee interfered with review
Sanofi has asked the FDA to pull its type 1 diabetes drug out of Commissioner Marty Makary’s new speedy drug review program.
STAT+: Color Health moving deeper into cancer services, complete with virtual ‘tumor boards’
Color Health, which coordinates cancer screening, is moving into a gap it observed — obtaining and coordinating actual cancer care.
Why the FDA is authorizing fruit-flavored vapes
Marty Makary says he was "skeptical initially" about flavored vapes but that age-gating technology could limit their use.
Sanofi asks to pull Tzield bid from FDA's controversial CNPV program: report
The FDA's Commissioner's National Priority Voucher program has been steeped in controversy since its inception. Now, Sanofi has asked that one of its applications be taken out of the fast-track program, according to Stat.
FDA rolls out 1-day assessment pilot in bid to refocus inspection resources
In a bid to better deploy its boots-on-the-ground resources, the FDA is rolling out a new pilot program, under which the regulator is leveraging “one-day inspectional assessments” to complement its traditional site visits.
Novo CEO cites pricing 'sweet spot' as Wegovy pill debuts with $355M quarter
After several consecutive quarters on the backfoot, Danish drug juggernaut Novo Nordisk is receiving warmer feedback on its starting performance in 2026, thanks in no small part to its head start over rival Eli Lilly in the burgeoning market for oral obesity therapies.
FDA blocks publication of COVID, shingles vaccine safety studies: NYT
The FDA-conducted studies reportedly found COVID vaccines and GSK's shingles vaccine Shringrix safe and effective, according to The New York Times.
Bayer diagnoses how to build trust in cell and gene therapies
Cell and gene therapy developers must build continuity of engagement to create trust in the modalities, according to a report by Bayer’s venture capital wing.
Touting $529B in savings over 10 years, White House looks to expand MFN deals with pharma
Following a series of “most favored nation” pricing deals with 17 large pharma companies, the Trump administration released a report Tuesday projecting potential $529 billion in savings from the policy over the next 10 years.
The timing is right for psychedelics manufacturer Optimi Health's IPO
Last month, when Optimi Health kicked off an initial public offering of 2.5 million shares, the timing couldn’t have been better for the Vancouver-based manufacturer of psychedelic drugs. With President Donald Trump recently signing an executive order to accelerate research and ease the restrictions on psychedelics, there is unprecedented buzz around the potential of the hallucinogenic drugs to tr
Novo Nordisk, Eli Lilly fined by French regulator over obesity drug promotions
As the promotion battle between old rivals Novo Nordisk and Eli Lilly heats up, regulators in France are reminding the world’s two biggest obesity drugmakers what happens when promotion goes too far.