J&J fleshes out US investment plan, telegraphing $1B cell therapy plant and 500 new jobs in PA
With $55 billion earmarked to bolster its U.S. operations, Johnson & Johnson is the latest drugmaker to zero in on expansion plans that are aimed, at least in part, at abating the Trump administration’s pharmaceutical tariff threats.
Recipharm focuses footprint with sale of Israel API plant, new CDMO partnership
As Recipharm continues to refine its footprint, the CDMO is selling its development and small-scale active pharmaceutical ingredient (API) manufacturing facility in Yavne, Israel, to Scinai Immunotherapeutics.
Senate HELP Committee chair pitches proposals for FDA reform
In his report, Senator Bill Cassidy suggested a slate of changes to the FDA to support broader drug access and to reduce regulatory burdens on drugmakers.
STAT+: Biotech startup raises $175 million to advance Alzheimer’s antibody therapy
Is there room for more Alzheimer’s antibody therapies on the market? Korsana Biosciences' investors think so.
This reengineered HPV vaccine trains T cells to hunt down cancer
Northwestern researchers have shown that when it comes to cancer vaccines, arrangement can be just as important as ingredients. By repositioning a small fragment of an HPV protein on a DNA-based nanovaccine, the team dramatically strengthened the immune system’s attack on HPV-driven tumors. One specific design slowed tumor growth, extended survival in animal models, and unleashed far more cancer-k
Sugary drinks linked to rising anxiety in teens
Sugary drinks may be linked to more than just physical health problems in teens. A new review of multiple studies found a consistent association between high consumption of beverages like soda, energy drinks, sweetened juices, and flavored milks and increased anxiety symptoms in adolescents.
Novartis heads to FDA with Rhapsido after phase 3 win in untapped chronic hives subtype
Less than half a year after winning an inaugural green light in chronic hives, Novartis’ oral BTK inhibitor Rhapsido is jockeying to expand its urticaria reach into a new indication where it has the potential to become the first targeted therapy.
Opinion: I was a Moderna exec when the Covid vaccine rolled out. That spirit of possibility is no more
“The pharmaceutical industry is not the enemy,” writes Richard Hughes IV, who was Moderna’s VP for public policy when the Covid vaccine rolled out.
STAT+: As oncologists ponder how to integrate AI-powered cancer tools, products are hitting the market
Oncologists say there is promise in new AI tools that can guide them when choosing between two plausible treatments.
Intermittent fasting fails to beat standard dieting for weight loss
Intermittent fasting has become one of the most talked-about weight loss trends in recent years, promising dramatic results with simple changes to when you eat. But a major Cochrane review suggests the reality may be far less exciting. After analyzing 22 clinical trials involving nearly 2,000 adults, researchers found that intermittent fasting did not produce significantly more weight loss than st
Viagra and shingles vaccine show surprising promise against Alzheimer’s
A major new study has spotlighted three familiar medicines that could take on an unexpected new role in the fight against Alzheimer’s disease — with a shingles vaccine emerging as the front-runner. After reviewing 80 existing drugs, an international panel of experts identified Zostavax, Viagra (sildenafil), and riluzole as the most promising candidates for repurposing.
Lilly chalks up another trial win for Zepbound-Taltz combo in bid to break down psoriasis, obesity 'silos'
Six weeks after Eli Lilly revealed the success of phase 3b trial testing a combination of Zepbound and Taltz in patients with psoriatic arthritis, the Indianapolis company has reported another trial victory with the combination treatment in patients with psoriasis.
With an assist from Shaq, Lilly joins Team USA's work to help Olympic athletes rebound from injury
Eli Lilly is partnering on Team USA’s push to help Olympic athletes hurdle the challenges of recovering from injury. And, with increased awareness of the program on the agenda, the drugmaker has enlisted former basketball star Shaquille O’Neal to help spread the word.
Breakthrough CRISPR system could reverse antibiotic resistance crisis
Antibiotic resistance is racing toward a global crisis, with “superbugs” projected to cause over 10 million deaths annually by 2050. Now, scientists at UC San Diego have unveiled a powerful new CRISPR-based tool that doesn’t just fight resistant bacteria—it can actively strip away their drug resistance. Inspired by gene drives used in insects, the technology spreads a genetic “fix” through bacteri
People who switched to cannabis drinks cut their alcohol use nearly in half
A new University at Buffalo study suggests cannabis-infused beverages could help some people cut back on alcohol. In a survey of cannabis users, those who drank cannabis beverages reported cutting their weekly alcohol intake roughly in half and binge drinking less often. Nearly two-thirds said they reduced or stopped drinking alcohol after starting cannabis drinks.
STAT+: At drugmakers’ forum, Oz gets a friendly embrace, while Makary faces tough questions
Two of health secretary Robert F. Kennedy Jr.’s top lieutenants struck decidedly different tones at a forum held Tuesday by the pharmaceutical industry group PhRMA.
One stem cell generates 14 million tumor-killing NK cells in major cancer breakthrough
Scientists in China have unveiled a breakthrough way to mass-produce powerful cancer-fighting immune cells in the lab. By engineering early-stage stem cells from cord blood—rather than trying to modify mature natural killer (NK) cells—they created a streamlined process that generates enormous numbers of highly potent NK cells, including CAR-equipped versions designed to hunt specific cancers.
Bayer agrees to $7.25 billion proposed settlement over thousands of Roundup cancer lawsuits
Bayer has agreed to $7.25 billion proposed settlement over thousands of lawsuits alleging the company failed to warn people that its popular weedkiller Roundup could cause cancer.
STAT+: A shakeup at HHS, a toast to bipartisanship, and a cheese poof war
You're reading the web edition of D.C. Diagnosis, STAT's guide to the ins and outs and oddities of health politics and policy
EyePoint scopes out new commercial chief to prepare for Duravyu launch
As it looks ahead to the potential launch of its sustained-delivery treatment Duravyu for wet age-related macular degeneration and diabetic macular edema, EyePoint has tapped a new commercial leader with experience heading up ophthalmology franchises at Genentech, Novartis and other drugmakers.