Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools.
A new nanodisc-based platform lets scientists study viral proteins in a form that closely mimics real viruses, revealing how antibodies truly recognize them. This approach uncovered hidden interactions in viruses like HIV and Ebola that traditional methods missed. By recreating the virus’s membrane environment, researchers can better understand how immune defenses work. The technique could speed u
“Even if not everybody is losing a ton of money right now, you're creating this culture of large numbers of gamblers,” Isaac Rose-Berman says on the First Opinion Podcast.
“Is ‘lack of education’ really what we think the problem is in prevention care?” a STAT reader asks.
Putting on weight earlier in life may be more dangerous than previously thought. Researchers found that early adulthood obesity significantly raises the risk of premature death, especially from major diseases like heart disease and diabetes. The longer the body carries excess weight, the greater the damage appears to be. Interestingly, cancer risk in women didn’t follow this pattern, suggesting ot
A major study suggests that when you eat could play a key role in staying lean. People who fast longer overnight and start their day with an early breakfast were more likely to have a lower BMI years later. Scientists think this is because eating earlier aligns better with the body’s internal clock. But skipping breakfast as part of intermittent fasting didn’t offer the same advantage—and may even
Losing your sense of smell might signal Alzheimer’s far earlier than expected. Scientists found that immune cells in the brain actively destroy smell-related nerve fibers after detecting abnormal signals on their surfaces. This damage begins in early stages of the disease, well before cognitive decline. The discovery could help identify at-risk patients sooner and improve treatment timing.
Researchers have uncovered why a rare blood clotting disorder can occur after certain COVID-19 vaccines or adenovirus infections. The immune system can mistakenly target a normal blood protein (PF4) after confusing it with a viral protein. This triggers clotting in extremely rare cases. The breakthrough means vaccines can now be redesigned to avoid this reaction while staying effective.
The Justice Department's actions on illegal vapes pales next to the scale of the problem, anti-smoking advocates say.
HHS secretary Robert F. Kennedy Jr. is continuing to reshape the CDC’s Advisory Committee on Immunization Practices in a way that’s setting off alarm bells for some experts.
A cancer drug candidate that, rightly or wrongly, became a flashpoint at FDA, fails on a second try at approval.
From new hires to departures, promotions and transfers, here are the latest comings and goings in the pharmaceutical industry.
The Trump administration this week acknowledged it made a significant error in figures it used to help justify a fraud probe into New York’s Medicaid program
CAR-T promise in autoimmunity, GSK's goodbye to leucovorin, and more biotech news
The second time is not the charm for Replimune’s melanoma candidate RP1. After spurning the immunotherapy last July, the FDA has now rejected the biotech’s resubmitted application.
And more pharmaceutical news from the Pharmalot campus via the Pharmalittle newsletter
A revised ACIP charter, sports betting and gambling addiction, and other health news from Morning Rounds
As geopolitics bring reshoring interest to a fever pitch, the United States Pharmacopeia (USP) is adding to the impetus for local drug production with a warning that homes in on the pharmaceutical building blocks known as key starting materials.
Novartis is making further workforce reductions at its U.S. headquarters in New Jersey, planning to remove 114 positions as the drugmaker rejigs its sales team for rare disease medicines.
Charles River Laboratories has backed an American Heart Association campaign, joining forces with the nonprofit on cardiovascular disease awareness, prevention and community health initiatives.