Scientists say we’ve been treating Alzheimer’s all wrong
Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward multi-pronged strategies, from gene editing to brain-cell rejuvenation and gut health interventions. The goal: stop treating Alzheimer’s as one disease and start tack
A common nutrient could supercharge cancer treatment
A common eye-health nutrient, zeaxanthin, may also help the body fight cancer more effectively. Scientists discovered it strengthens T cells and enhances the impact of immunotherapy treatments. Found in everyday vegetables and supplements, it’s safe, accessible, and shows strong potential as a cancer therapy booster. Human trials are the next step.
Envision hires ConcertAI, IQVIA alum Nick Jones as its med comms president
Envision Pharma Group has hired clinical research veteran Nick Jones as president of its Envision Medical Communications (EMC) business.
The top 10 pharma R&D budgets of 2025
The wait is over. Fierce Biotech has unveiled its ranking of the top 10 pharma R&D budgets of 2025. In this episode of "The Top Line," Darren Incorvaia and Eric Sagonowsky break down the biggest trends and what’s changed year over year.
Bial launches ‘Dialogues with Parkinson’s’ campaign aimed at identifying early symptoms
Portuguese biopharma Bial is launching a year-long disease awareness campaign that’s intended to boost understanding of Parkinson’s disease and its often subtle and early-stage symptoms.
How sports betting apps hook users
In this week's STATus Report, host Alex Hogan dives into how sports betting apps hook users — and how he himself fell for some too-good-to-be-true promotions.
Opinion: What public health can learn from the MAHA movement
“What MAHA has built, in a relatively short time, is social capital,” writes Monica L. Wang.
Opinion: I’m a MAHA activist. I went into the public health lion’s den — and it changed how I think
“In my most honest of moments, what I want from the medical community is the chance to trust it again,” a MAHA advocate writes.
Novartis pumps up community health footprint to tackle heart disease and cancer
Novartis is launching a three-front push to close healthcare gaps in heart disease and cancer, expanding initiatives with the goal of roughly tripling their footprint by 2030.
Abbott survey finds ‘information overload, confusion and cost’ affecting health choices in US
Too much information, uncertainty and financial worries are hitting Americans when it comes to making important choices for their health.
FDA accuses Amneal, BioCorRx of producing ‘false and misleading’ drug promos
Amneal and BioCorRx have earned the ire of the FDA’s Office of Prescription Drug Promotion (OPDP), with both being hit by accusations of violating the agency’s drug marketing rules.
Scientists finally uncover why promising cancer drugs keep failing
Cancer drugs known as BET inhibitors once looked like a breakthrough, but in real patients they’ve often fallen short. New research reveals a key reason why: two closely related proteins, BRD2 and BRD4, don’t actually do the same job. Instead, BRD2 acts like a “stage manager,” preparing genes for activation, while BRD4 triggers the final step that turns them on. By blocking both at once, current d
Goodbye colonoscopy? New stool test detects 90% of colorectal cancers
A breakthrough in microbiome research could change how colorectal cancer is detected—no colonoscopy required. Scientists used AI to map gut bacteria at an unprecedented level of detail, revealing subtle microbial patterns linked to cancer. By analyzing simple stool samples, their method identified 90% of cases, rivaling one of medicine’s most trusted diagnostic tools.
STAT+: Top health officials highlight efforts to make medical records more portable
Health tech companies are working to make medical records more portable, but so far, the effort is voluntary.
New rules for CDC vaccine panel aim to address lawsuit, empower Kennedy’s allies
The panel had become a flashpoint as RFK Jr.'s health department worked to limit the number of recommended childhood shots.
A new trick for old science, and biotech VCs’ scrambled playbook
This week on "The Readout LOUD": Why is old exon science getting new traction? What’s unsettling biotech VCs? And who will be the next CEO of PhRMA?
STAT+: A new health care blueprint from a key Democratic think tank
Democrats are focused on health care affordability as costs keep climbing.
Fierce Pharma Asia—Takeda-Denali split-up; Merck, Zhifei's revised deal; Shionogi's made-in-US plan
Takeda ended its neurogenerative disease partnership with Denali Therapeutics. Merck & Co. and Zhifei scrapped a minimum purchase requirement in their vaccine distribution agreement. Shionogi secured funding from the U.S. government to boost the domestic supply of an antibiotic. And more.
STAT+: 5 years after lupus breakthrough, CAR-T is still surprising autoimmunity researchers
CAR-T therapy is toting up more remissions in autoimmune disease, and generating a flood of experimentation and investment.
Vanda initiates study of motion sickness drug Nereus in GLP-1 users
Vanda is kicking off a phase 3 trial which will evaluate the efficacy and safety of its newly approved motion sickness drug Nereus in patients receiving a high dose of a GLP-1 agonist. The primary endpoint is the proportion of patients free from vomiting episodes.